Design, Synthesis, and In Vitro Enzymatic Evaluation of Novel Flavone Derivatives as Dual COX-2/5-LOX Inhibitors Supported by Molecular Docking and ADMET Analysis.
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| Title: | Design, Synthesis, and In Vitro Enzymatic Evaluation of Novel Flavone Derivatives as Dual COX-2/5-LOX Inhibitors Supported by Molecular Docking and ADMET Analysis. |
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| Authors: | Fraj E; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Elbouzidi A; Laboratory for Agricultural Production Improvement, Biotechnology, and Environment (LAPABE), Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Bouammali H; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Jaouani H; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Bourhou C; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Addi M; Laboratory for Agricultural Production Improvement, Biotechnology, and Environment (LAPABE), Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Zughaier SM; College of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar., Challioui A; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Touzani R; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco., Bouammali B; Laboratory of applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco. |
| Source: | Current issues in molecular biology [Curr Issues Mol Biol] 2026 Feb 25; Vol. 48 (3). Date of Electronic Publication: 2026 Feb 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100931761 Publication Model: Electronic Cited Medium: Internet ISSN: 1467-3045 (Electronic) Linking ISSN: 14673037 NLM ISO Abbreviation: Curr Issues Mol Biol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1467-3045 |
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| DOI: | 10.3390/cimb48030243 |
