BMP4-driven morphogenetic reprogramming sustains EGFR-TKI resistance via SOX2 suppression and EMT activation.
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| Title: | BMP4-driven morphogenetic reprogramming sustains EGFR-TKI resistance via SOX2 suppression and EMT activation. |
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| Authors: | Chen A; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Xie DJ; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Jhu YW; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Lin YJ; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Wu DY; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan., Yan SL; PharmaEssentia Corporation, Taipei, Taiwan., Chou YT; Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan. Electronic address: ytchou@life.nthu.edu.tw., Ko JC; Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan. Electronic address: e1205470@ms22.hinet.net. |
| Source: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 May; Vol. 198, pp. 119281. Date of Electronic Publication: 2026 Mar 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1950-6007 |
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| DOI: | 10.1016/j.biopha.2026.119281 |
