Subchondral H-type blood vessel formation aggravates articular cartilage degeneration through LEP-LEPR axis.

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Title: Subchondral H-type blood vessel formation aggravates articular cartilage degeneration through LEP-LEPR axis.
Authors: Yu C; Department of Orthopaedic Surgery, The University-Town Hospital of Chongqing Medical University, Chongqing, China.; Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL, United States., Zhao X; Department of Orthopaedic Surgery, The University-Town Hospital of Chongqing Medical University, Chongqing, China., Luo S; Department of Orthopaedic Surgery, The University-Town Hospital of Chongqing Medical University, Chongqing, China., Qin J; Department of Orthopaedic Surgery, The University-Town Hospital of Chongqing Medical University, Chongqing, China., Li J; Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL, United States.; Department of Oncology, School of Clinical Medicine, The Affiliated Hospital, Shandong Second Medical University, Weifang, China.
Source: Frontiers in medicine [Front Med (Lausanne)] 2026 Mar 13; Vol. 13, pp. 1751127. Date of Electronic Publication: 2026 Mar 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-858X
DOI:10.3389/fmed.2026.1751127