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Spatial transcriptomic profiling reveals body site-specific inflammatory differences in psoriasis lesions.

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Title: Spatial transcriptomic profiling reveals body site-specific inflammatory differences in psoriasis lesions.
Authors: Emmanuel T; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Ben Abdallah H; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Nielsen MM; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark., Ignatov B; Department of Medicine, Karolinska Institutet and PO Reuma/Hud/Gastro, Karolinska University Hospital, Stockholm, Sweden.; LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark., Baez E; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Andersen AS; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Waaben L; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Boye M; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Kaaber I; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Boonen DS; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Petersen SR; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Steiniche T; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark., Bregnhøj A; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Eidsmo L; Department of Medicine, Karolinska Institutet and PO Reuma/Hud/Gastro, Karolinska University Hospital, Stockholm, Sweden.; LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark., Iversen L; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Vestergaard C; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Johansen C; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 12; Vol. 17, pp. 1706701. Date of Electronic Publication: 2026 Mar 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Emmanuel+T%22">Emmanuel T</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Ben+Abdallah+H%22">Ben Abdallah H</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Nielsen+MM%22">Nielsen MM</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Ignatov+B%22">Ignatov B</searchLink>; Department of Medicine, Karolinska Institutet and PO Reuma/Hud/Gastro, Karolinska University Hospital, Stockholm, Sweden.; LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Baez+E%22">Baez E</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Andersen+AS%22">Andersen AS</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Waaben+L%22">Waaben L</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Boye+M%22">Boye M</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Kaaber+I%22">Kaaber I</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Boonen+DS%22">Boonen DS</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Petersen+SR%22">Petersen SR</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Steiniche+T%22">Steiniche T</searchLink>; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Bregnhøj+A%22">Bregnhøj A</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Eidsmo+L%22">Eidsmo L</searchLink>; Department of Medicine, Karolinska Institutet and PO Reuma/Hud/Gastro, Karolinska University Hospital, Stockholm, Sweden.; LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Iversen+L%22">Iversen L</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Vestergaard+C%22">Vestergaard C</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Johansen+C%22">Johansen C</searchLink>; Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
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