Risk of obesity, diabetes, hypertension, and major adverse cardiovascular events after a switch to an integrase inhibitor: a target trial emulation in REPRIEVE.
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| Title: | Risk of obesity, diabetes, hypertension, and major adverse cardiovascular events after a switch to an integrase inhibitor: a target trial emulation in REPRIEVE. |
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| Authors: | Kileel EM; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Malvestutto CD; Division of Infectious Diseases, Ohio State University Medical Center, Columbus, OH, USA., Zanni MV; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Davies-Smith E; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA., Fichtenbaum CJ; Division of Infectious Diseases, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA., Lake JE; Department of Medicine, McGovern Medical School, Houston, TX, USA., Lo J; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Aberg JA; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Martinez E; Infectious Diseases Service, Hospital Clinic and University of Barcelona, Barcelona, Spain; CIBER de Enfermedades Infecciosas, Institute de Salud Carlos III, Madrid, Spain., Patel K; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA., Bloomfield GS; Department of Medicine, Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, NC, USA., Chu SM; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Awwad A; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Diggs MR; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Lu AB; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Bares SH; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA., Berrner D; Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco at Zuckerberg San Francisco General Hospital, San Francisco, CA, USA., Smieja M; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada., Okeke NL; Department of Population Health Sciences and Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Kumar P; Division of Infectious Diseases and Travel Medicine, Georgetown University School of Medicine, Washington, DC, USA., João E; Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil., Currier JS; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Lu MT; Cardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Fox MP; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Brennan AT; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Douglas PS; Duke University Research Institute, Duke University School of Medicine, Durham, NC, USA., Grinspoon SK; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: sgrinspoon@mgh.harvard.edu., Ribaudo HJ; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA. |
| Source: | The lancet. HIV [Lancet HIV] 2026 May; Vol. 13 (5), pp. e306-e315. Date of Electronic Publication: 2026 Mar 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101645355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3018 (Electronic) Linking ISSN: 23523018 NLM ISO Abbreviation: Lancet HIV Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41911941 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Risk of obesity, diabetes, hypertension, and major adverse cardiovascular events after a switch to an integrase inhibitor: a target trial emulation in REPRIEVE. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kileel+EM%22">Kileel EM</searchLink>; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Malvestutto+CD%22">Malvestutto CD</searchLink>; Division of Infectious Diseases, Ohio State University Medical Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Zanni+MV%22">Zanni MV</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Davies-Smith+E%22">Davies-Smith E</searchLink>; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fichtenbaum+CJ%22">Fichtenbaum CJ</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Lake+JE%22">Lake JE</searchLink>; Department of Medicine, McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lo+J%22">Lo J</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Aberg+JA%22">Aberg JA</searchLink>; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+E%22">Martinez E</searchLink>; Infectious Diseases Service, Hospital Clinic and University of Barcelona, Barcelona, Spain; CIBER de Enfermedades Infecciosas, Institute de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Patel+K%22">Patel K</searchLink>; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bloomfield+GS%22">Bloomfield GS</searchLink>; Department of Medicine, Duke Global Health Institute and Duke Clinical Research Institute, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Chu+SM%22">Chu SM</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Awwad+A%22">Awwad A</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Diggs+MR%22">Diggs MR</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+AB%22">Lu AB</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bares+SH%22">Bares SH</searchLink>; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Berrner+D%22">Berrner D</searchLink>; Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco at Zuckerberg San Francisco General Hospital, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Smieja+M%22">Smieja M</searchLink>; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Okeke+NL%22">Okeke NL</searchLink>; Department of Population Health Sciences and Department of Medicine, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Division of Infectious Diseases and Travel Medicine, Georgetown University School of Medicine, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22João+E%22">João E</searchLink>; Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Currier+JS%22">Currier JS</searchLink>; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+MT%22">Lu MT</searchLink>; Cardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fox+MP%22">Fox MP</searchLink>; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Brennan+AT%22">Brennan AT</searchLink>; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Douglas+PS%22">Douglas PS</searchLink>; Duke University Research Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Grinspoon+SK%22">Grinspoon SK</searchLink>; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: sgrinspoon@mgh.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Ribaudo+HJ%22">Ribaudo HJ</searchLink>; Center for Biostatistics in AIDS Research, Harvard T H Chan School of Public Health, Boston, MA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101645355%22">The lancet. HIV</searchLink> [Lancet HIV] 2026 May; Vol. 13 (5), pp. e306-e315. <i>Date of Electronic Publication: </i>2026 Mar 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101645355 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-3018 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223523018%22">23523018 </searchLink><i>NLM ISO Abbreviation: </i>Lancet HIV <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41911941 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S2352-3018(25)00354-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e306 Titles: – TitleFull: Risk of obesity, diabetes, hypertension, and major adverse cardiovascular events after a switch to an integrase inhibitor: a target trial emulation in REPRIEVE. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kileel EM – PersonEntity: Name: NameFull: Malvestutto CD – PersonEntity: Name: NameFull: Zanni MV – PersonEntity: Name: NameFull: Davies-Smith E – PersonEntity: Name: NameFull: Fichtenbaum CJ – PersonEntity: Name: NameFull: Lake JE – PersonEntity: Name: NameFull: Lo J – PersonEntity: Name: NameFull: Aberg JA – PersonEntity: Name: NameFull: Martinez E – PersonEntity: Name: NameFull: Patel K – PersonEntity: Name: NameFull: Bloomfield GS – PersonEntity: Name: NameFull: Chu SM – PersonEntity: Name: NameFull: Awwad A – PersonEntity: Name: NameFull: Diggs MR – PersonEntity: Name: NameFull: Lu AB – PersonEntity: Name: NameFull: Bares SH – PersonEntity: Name: NameFull: Berrner D – PersonEntity: Name: NameFull: Smieja M – PersonEntity: Name: NameFull: Okeke NL – PersonEntity: Name: NameFull: Kumar P – PersonEntity: Name: NameFull: João E – PersonEntity: Name: NameFull: Currier JS – PersonEntity: Name: NameFull: Lu MT – PersonEntity: Name: NameFull: Fox MP – PersonEntity: Name: NameFull: Brennan AT – PersonEntity: Name: NameFull: Douglas PS – PersonEntity: Name: NameFull: Grinspoon SK – PersonEntity: Name: NameFull: Ribaudo HJ IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2026 May Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2352-3018 Numbering: – Type: volume Value: 13 – Type: issue Value: 5 Titles: – TitleFull: The lancet. HIV Type: main |
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