The RASSF1C-HIF-1α axis drives macrophage lipid metabolism to promote pancreatic cancer.

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Title: The RASSF1C-HIF-1α axis drives macrophage lipid metabolism to promote pancreatic cancer.
Authors: Zhan T; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Huang M; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Chen M; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China.; Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China., Chen W; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Wang Y; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Chen X; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Zou Y; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Liu M; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China., Zhu Q; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China. 12858590@qq.com., Tian X; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China. hcwy100@163.com., Han Z; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China. 422435466@qq.com., Huang X; Department of Gastroenterology, Tongren hospital of WuHan University(WuHan Third Hospital), Wuhan, China. 13297056720@163.com.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 30; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08609-0