Bayesian modelling demonstrates clinically relevant heterogeneity in Tau PET patterns in Alzheimer's disease.

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Title: Bayesian modelling demonstrates clinically relevant heterogeneity in Tau PET patterns in Alzheimer's disease.
Authors: Xia Y; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands., Johnson K; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Fakhri GE; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA., Guehl NJ; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA., van de Giessen E; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands.; Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands., Coomans EC; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands., Pijnenburg YAL; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands., Ossenkoppele R; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands., Groot C; Department of Neurology, Alzheimer Center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, Netherlands. c.groot3@amsterdamumc.nl.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands. c.groot3@amsterdamumc.nl.
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Jun; Vol. 53 (7), pp. 4664-4676. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1619-7089
DOI:10.1007/s00259-026-07868-5