Development of a QSAR model for predicting PPARα activation by PFAS based on human in vitro data of a comprehensive panel of legacy and novel PFAS.
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| Title: | Development of a QSAR model for predicting PPARα activation by PFAS based on human in vitro data of a comprehensive panel of legacy and novel PFAS. |
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| Authors: | Alker W; Department Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Str. 8-10, 10589, Berlin, Germany., Tsiros P; School of Chemical Engineering, National Technical University of Athens, 9 Iroon Polytechniou Str, 15772, Athens, Greece., Sarimveis H; School of Chemical Engineering, National Technical University of Athens, 9 Iroon Polytechniou Str, 15772, Athens, Greece., Braeuning A; Department Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Str. 8-10, 10589, Berlin, Germany., Buhrke T; Department Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Str. 8-10, 10589, Berlin, Germany. thorsten.buhrke@bfr.bund.de. |
| Source: | Archives of toxicology [Arch Toxicol] 2026 May; Vol. 100 (5), pp. 2047-2067. Date of Electronic Publication: 2026 Mar 31. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1432-0738 |
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| DOI: | 10.1007/s00204-026-04359-2 |