Bridging mechanism and clinic: unlocking the full potential of oncolytic virus-based immunotherapy.

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Title: Bridging mechanism and clinic: unlocking the full potential of oncolytic virus-based immunotherapy.
Authors: Hua X; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China., Tang H; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China., Liang K; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China., Li J; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China. oncogene@bjmu.edu.cn.; Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, 52 Fucheng Road, Beijing, 100142, China. oncogene@bjmu.edu.cn., Zhang X; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China. zhangxiaotian@bjmu.edu.cn.; Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, 52 Fucheng Road, Beijing, 100142, China. zhangxiaotian@bjmu.edu.cn.; Department of Gastrointestinal Oncology, Peking University Cancer Hospital (Inner Mongolia Campus)/Affiliated Cancer Hospital of Inner Mongolia Medical University, Hohhot, China. zhangxiaotian@bjmu.edu.cn., Shen L; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China. shenlin@bjmu.edu.cn.; Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, 52 Fucheng Road, Beijing, 100142, China. shenlin@bjmu.edu.cn., Zhang C; Department of Gastrointestinal Oncology, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Fu-Cheng Road 52, Hai-Dian District, 100142, Beijing, China. qenya_z@bjmu.edu.cn.; Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, 52 Fucheng Road, Beijing, 100142, China. qenya_z@bjmu.edu.cn.
Source: Molecular cancer [Mol Cancer] 2026 Mar 31; Vol. 25 (1). Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4598
DOI:10.1186/s12943-026-02651-4