Integration of gene expression profiling and mutation analysis via RNA sequencing: transitioning the 95-gene classifier to a next-generation platform in early-stage HR+/HER2- breast cancer.

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Title: Integration of gene expression profiling and mutation analysis via RNA sequencing: transitioning the 95-gene classifier to a next-generation platform in early-stage HR+/HER2- breast cancer.
Authors: Kato C; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sota Y; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan., Kitano S; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Watanabe A; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Nishida M; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Motonari D; SYSMEX Corporation, Kobe, Hyogo, Japan., Saito Y; SYSMEX Corporation, Kobe, Hyogo, Japan., Kobayashi M; SYSMEX Corporation, Kobe, Hyogo, Japan., Morita M; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sakaguchi K; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Shimazu K; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan., Naoi Y; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. naoi@koto.kpu-m.ac.jp.
Source: Breast cancer (Tokyo, Japan) [Breast Cancer] 2026 May; Vol. 33 (3), pp. 722-735. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Maruzen Co Country of Publication: Japan NLM ID: 100888201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-4233 (Electronic) Linking ISSN: 13406868 NLM ISO Abbreviation: Breast Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1880-4233
DOI:10.1007/s12282-026-01854-3