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Integration of gene expression profiling and mutation analysis via RNA sequencing: transitioning the 95-gene classifier to a next-generation platform in early-stage HR+/HER2- breast cancer.

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Title: Integration of gene expression profiling and mutation analysis via RNA sequencing: transitioning the 95-gene classifier to a next-generation platform in early-stage HR+/HER2- breast cancer.
Authors: Kato C; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sota Y; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan., Kitano S; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Watanabe A; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Nishida M; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Motonari D; SYSMEX Corporation, Kobe, Hyogo, Japan., Saito Y; SYSMEX Corporation, Kobe, Hyogo, Japan., Kobayashi M; SYSMEX Corporation, Kobe, Hyogo, Japan., Morita M; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sakaguchi K; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Shimazu K; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan., Naoi Y; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. naoi@koto.kpu-m.ac.jp.
Source: Breast cancer (Tokyo, Japan) [Breast Cancer] 2026 May; Vol. 33 (3), pp. 722-735. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Maruzen Co Country of Publication: Japan NLM ID: 100888201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-4233 (Electronic) Linking ISSN: 13406868 NLM ISO Abbreviation: Breast Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Integration of gene expression profiling and mutation analysis via RNA sequencing: transitioning the 95-gene classifier to a next-generation platform in early-stage HR+/HER2- breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Kato+C%22">Kato C</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Sota+Y%22">Sota Y</searchLink>; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kitano+S%22">Kitano S</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+A%22">Watanabe A</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+M%22">Nishida M</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Motonari+D%22">Motonari D</searchLink>; SYSMEX Corporation, Kobe, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+Y%22">Saito Y</searchLink>; SYSMEX Corporation, Kobe, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+M%22">Kobayashi M</searchLink>; SYSMEX Corporation, Kobe, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Morita+M%22">Morita M</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Sakaguchi+K%22">Sakaguchi K</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Shimazu+K%22">Shimazu K</searchLink>; Department of Breast and Endocrine Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Naoi+Y%22">Naoi Y</searchLink>; Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. naoi@koto.kpu-m.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22100888201%22">Breast cancer (Tokyo, Japan)</searchLink> [Breast Cancer] 2026 May; Vol. 33 (3), pp. 722-735. <i>Date of Electronic Publication: </i>2026 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Maruzen+Co%22">Maruzen Co </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>100888201 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-4233 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213406868%22">13406868 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12282-026-01854-3
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              Text: 2026 May
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