Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model.
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| Title: | Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model. |
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| Authors: | Leite JA; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. jeffersonleite@micro.ufrj.br.; Department of Immunology, Institute of Microbiology Paulo de Góes, Center of Health Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil. jeffersonleite@micro.ufrj.br.; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany. jeffersonleite@micro.ufrj.br., Bos NN; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Division of Nephrology, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil., Menezes-Silva L; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Martins da Silva E; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Silva Leandro GD; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil., Moreira de Goes GC; Laboratory of Cheminformatics (LCi), Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil., da Silva P; Ann Romney Center for Neurologic Diseases, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA., Oliveira S; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., de Almeida Santos ES; Institute of Immunology, Rostock University Medical Center, Rostock, Germany., Ranfley H; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Palagi I; Division of Nephrology, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil., Andrade-Silva M; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Ferreira CP; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Nery Neto JAO; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Yuji Yariwake V; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Cipelli M; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Leocata B; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Gonçalves T; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Gabry da Silveira A; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Baroni S; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Weiner HL; Ann Romney Center for Neurologic Diseases, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA., Hofmann TG; Institute of Toxicology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Scheu S; School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil., Neves BJ; Institute of Immunology, Rostock University Medical Center, Rostock, Germany., de Souza-Pinto NC; Laboratory of Cheminformatics (LCi), Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil., Colli LM; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Waisman A; Division of Nephrology, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil., Marcia Muxel S; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil., Menck CFM; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil., Câmara NOS; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. niels@icb.usp.br.; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. niels@icb.usp.br. |
| Source: | Nature communications [Nat Commun] 2026 Apr 01; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-69914-y |
