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NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction.

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Title: NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction.
Authors: Cohen R; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Duval V; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Al-Rifai R; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Maryam S; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany., Santos-Zas I; Laboratorio de Endocrinología Celular, Área de Endocrinología Molecular y Cellular Instituto de Investigación Sanitaria de Santiago, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, Spain., Braik R; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Diedisheim M; Clinique Saint Gatien Alliance (NCT + ), Saint-Cyr-sur-Loire, France, INSERM U1151, Necker Enfants Malades (INEM), IMMEDIAB Laboratory, Paris, France., Jouve C; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Nicoletti S; Institut Imagine, INSERM U1163, CNRS ERL 8254, Sorbonne Paris-Cité, Laboratoire d'Excellence GR-Ex, Université Paris Cité, Paris, France., Thietart S; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Guyon T; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Chetrit L; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Kral M; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Döring Y; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland., Weber C; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Loupy A; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Domenge O; CIC1418 and DMU CARTE, AP-HP, Hôpital Européen Georges-Pompidou, Paris, France., Livrozet M; CIC1418 and DMU CARTE, AP-HP, Hôpital Européen Georges-Pompidou, Paris, France., Hulot JS; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Sakalli ET; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany., Rizzo G; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany., Saliba AE; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Center for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany., Piollet M; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany., Bruneval P; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Tedgui A; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Taleb S; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Hermine O; Institut Imagine, INSERM U1163, CNRS ERL 8254, Sorbonne Paris-Cité, Laboratoire d'Excellence GR-Ex, Université Paris Cité, Paris, France., Wicks I; Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, University of Melbourne, Parkville, Melbourne, VIC, Australia., Silvestre JS; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France., Hayat S; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany., Cochain C; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany., Vivier E; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France., Ait-Oufella H; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France. hafid.aitoufella@inserm.fr.; Sorbonne Université, Service de médecine intensive-Réanimation, Assistance Publique, Hôpitaux de Paris, Paris, France. hafid.aitoufella@inserm.fr.
Source: Nature communications [Nat Commun] 2026 Apr 01; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction.
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  Data: <searchLink fieldCode="AU" term="%22Cohen+R%22">Cohen R</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Duval+V%22">Duval V</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Al-Rifai+R%22">Al-Rifai R</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Maryam+S%22">Maryam S</searchLink>; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Santos-Zas+I%22">Santos-Zas I</searchLink>; Laboratorio de Endocrinología Celular, Área de Endocrinología Molecular y Cellular Instituto de Investigación Sanitaria de Santiago, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Braik+R%22">Braik R</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Diedisheim+M%22">Diedisheim M</searchLink>; Clinique Saint Gatien Alliance (NCT + ), Saint-Cyr-sur-Loire, France, INSERM U1151, Necker Enfants Malades (INEM), IMMEDIAB Laboratory, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jouve+C%22">Jouve C</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nicoletti+S%22">Nicoletti S</searchLink>; Institut Imagine, INSERM U1163, CNRS ERL 8254, Sorbonne Paris-Cité, Laboratoire d'Excellence GR-Ex, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Thietart+S%22">Thietart S</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guyon+T%22">Guyon T</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chetrit+L%22">Chetrit L</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kral+M%22">Kral M</searchLink>; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Döring+Y%22">Döring Y</searchLink>; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Weber+C%22">Weber C</searchLink>; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich (LMU), Munich, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Loupy+A%22">Loupy A</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Domenge+O%22">Domenge O</searchLink>; CIC1418 and DMU CARTE, AP-HP, Hôpital Européen Georges-Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Livrozet+M%22">Livrozet M</searchLink>; CIC1418 and DMU CARTE, AP-HP, Hôpital Européen Georges-Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hulot+JS%22">Hulot JS</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Sakalli+ET%22">Sakalli ET</searchLink>; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rizzo+G%22">Rizzo G</searchLink>; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Saliba+AE%22">Saliba AE</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Center for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Piollet+M%22">Piollet M</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bruneval+P%22">Bruneval P</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tedgui+A%22">Tedgui A</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Taleb+S%22">Taleb S</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hermine+O%22">Hermine O</searchLink>; Institut Imagine, INSERM U1163, CNRS ERL 8254, Sorbonne Paris-Cité, Laboratoire d'Excellence GR-Ex, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Wicks+I%22">Wicks I</searchLink>; Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, University of Melbourne, Parkville, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Silvestre+JS%22">Silvestre JS</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hayat+S%22">Hayat S</searchLink>; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Cochain+C%22">Cochain C</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France.; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vivier+E%22">Vivier E</searchLink>; Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Ait-Oufella+H%22">Ait-Oufella H</searchLink>; Université Paris Cité, INSERM U970, Paris Cardiovascular Research Center, Paris, France. hafid.aitoufella@inserm.fr.; Sorbonne Université, Service de médecine intensive-Réanimation, Assistance Publique, Hôpitaux de Paris, Paris, France. hafid.aitoufella@inserm.fr.
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