Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.

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Title: Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.
Authors: Lee JJ; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Zhang J; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chew SC; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore., Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Xu L; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kong JC; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Grigoryev F; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chung AY; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Teo JY; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Bonney G; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Wang Y; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. yulan.wang@ntu.edu.sg.; Human Phenome Institute, Fudan University, Shanghai, China. yulan.wang@ntu.edu.sg., Loo LH; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. loolh@a-star.edu.sg., Chow PK; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.
Source: Molecular systems biology [Mol Syst Biol] 2026 Jul; Vol. 22 (7), pp. 1132-1160. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1744-4292
DOI:10.1038/s44320-026-00205-w