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Cellular sensor DAP5 decodes Betacoronaviral NSP5 to drive virus-induced senescence.

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Title: Cellular sensor DAP5 decodes Betacoronaviral NSP5 to drive virus-induced senescence.
Authors: Lu Y; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China., Xiao J; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Tianjin Institute of Immunology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Wang J; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China., Meng Z; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China., Fan G; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China., Zheng J; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China., Yu M; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing Institute of Infectious Diseases, Beijing Key Laboratory of Viral Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China., Wang X; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing Institute of Infectious Diseases, Beijing Key Laboratory of Viral Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China., Li L; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 17; Vol. 17, pp. 1768183. Date of Electronic Publication: 2026 Mar 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cellular sensor DAP5 decodes Betacoronaviral NSP5 to drive virus-induced senescence.
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  Data: <searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Xiao+J%22">Xiao J</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Tianjin Institute of Immunology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Meng+Z%22">Meng Z</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Fan+G%22">Fan G</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Yu+M%22">Yu M</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing Institute of Infectious Diseases, Beijing Key Laboratory of Viral Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing Institute of Infectious Diseases, Beijing Key Laboratory of Viral Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Tianjin Institute of Immunology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), State Key Laboratory of Experimental Hematology, Department of Immunology, Tianjin Medical University, Tianjin, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Mar 17; Vol. 17, pp. 1768183. <i>Date of Electronic Publication: </i>2026 Mar 17 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar 17
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