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Effects of Elexacaftor/Tezacaftor/Ivacaftor on cough frequency, physical activity patterns, and sleep quality in adolescents and adults with cystic fibrosis.

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Title: Effects of Elexacaftor/Tezacaftor/Ivacaftor on cough frequency, physical activity patterns, and sleep quality in adolescents and adults with cystic fibrosis.
Authors: Van Braeckel E; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. Electronic address: Eva.VanBraeckel@UGent.be., Braun AT; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA., Simmonds NJ; National Heart and Lung Institute, Imperial College London UK, Royal Brompton Hospital, part of Guy's and St Thomas' NHS Foundation Trust, London, UK., Barry PJ; Manchester University NHS Foundation Trust, Manchester, UK; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK., Davies JC; National Heart and Lung Institute, Imperial College London UK, Royal Brompton Hospital, part of Guy's and St Thomas' NHS Foundation Trust, London, UK., Egan ME; Yale University, New Haven, CT, USA., Lapey A; Massachusetts General Hospital, Boston, MA, USA., Mall MA; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany; German Center for Lung Research (DZL), associated partner site, Berlin, Germany; German Center for Child and Adolescent Health (DZKJ), partner site Berlin, Berlin, Germany; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin, Germany., McKone EF; St Vincent's University Hospital, Dublin, Ireland., Peckham D; St James's University Hospital, Leeds, UK., Proesmans M; University Hospital of Leuven, Leuven, Belgium., Ramsey B; Seattle Children's Hospital, Seattle, WA, USA., Santamaria SV; Hospital Ramón y Cajal, Madrid, Spain., Smith D; The Prince Charles Hospital, Brisbane, Queensland, Australia., Taylor-Cousar JL; National Jewish Health, Denver, CO, USA., Tullis E; St Michael's Hospital, Toronto, Ontario, Canada., De Wachter E; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium., Withers N; Royal Devon United Hospital NHS Foundation Trust, Exeter, UK., Ahluwalia N; Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Conner S; Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Jennings M; Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Lou Y; Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Weinstock TG; Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Keating D; Alfred Health, and Monash University, Melbourne, Victoria, Australia.
Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2026 Mar 31. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of Elexacaftor/Tezacaftor/Ivacaftor on cough frequency, physical activity patterns, and sleep quality in adolescents and adults with cystic fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Van+Braeckel+E%22">Van Braeckel E</searchLink>; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. Electronic address: Eva.VanBraeckel@UGent.be.<br /><searchLink fieldCode="AU" term="%22Braun+AT%22">Braun AT</searchLink>; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Simmonds+NJ%22">Simmonds NJ</searchLink>; National Heart and Lung Institute, Imperial College London UK, Royal Brompton Hospital, part of Guy's and St Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Barry+PJ%22">Barry PJ</searchLink>; Manchester University NHS Foundation Trust, Manchester, UK; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Davies+JC%22">Davies JC</searchLink>; National Heart and Lung Institute, Imperial College London UK, Royal Brompton Hospital, part of Guy's and St Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Egan+ME%22">Egan ME</searchLink>; Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lapey+A%22">Lapey A</searchLink>; Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mall+MA%22">Mall MA</searchLink>; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany; German Center for Lung Research (DZL), associated partner site, Berlin, Germany; German Center for Child and Adolescent Health (DZKJ), partner site Berlin, Berlin, Germany; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22McKone+EF%22">McKone EF</searchLink>; St Vincent's University Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Peckham+D%22">Peckham D</searchLink>; St James's University Hospital, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Proesmans+M%22">Proesmans M</searchLink>; University Hospital of Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ramsey+B%22">Ramsey B</searchLink>; Seattle Children's Hospital, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Santamaria+SV%22">Santamaria SV</searchLink>; Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Smith+D%22">Smith D</searchLink>; The Prince Charles Hospital, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Taylor-Cousar+JL%22">Taylor-Cousar JL</searchLink>; National Jewish Health, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Tullis+E%22">Tullis E</searchLink>; St Michael's Hospital, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22De+Wachter+E%22">De Wachter E</searchLink>; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Withers+N%22">Withers N</searchLink>; Royal Devon United Hospital NHS Foundation Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Ahluwalia+N%22">Ahluwalia N</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Conner+S%22">Conner S</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jennings+M%22">Jennings M</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lou+Y%22">Lou Y</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weinstock+TG%22">Weinstock TG</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Keating+D%22">Keating D</searchLink>; Alfred Health, and Monash University, Melbourne, Victoria, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101128966%22">Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society</searchLink> [J Cyst Fibros] 2026 Mar 31. <i>Date of Electronic Publication: </i>2026 Mar 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101128966 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215691993%22">15691993 </searchLink><i>NLM ISO Abbreviation: </i>J Cyst Fibros <i>Subsets: </i>MEDLINE
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