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Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1+ nociceptive sensory neuron activation.

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Title: Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1+ nociceptive sensory neuron activation.
Authors: Carneiro JA; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Bianchini BHS; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Martelossi-Cebinelli G; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Artero NA; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Maximiano TKE; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Franciosi A; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Dionisio AM; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Yaekashi KM; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Carvalho TT; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., da Silva MDV; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Rasquel-Oliveira FS; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA., Zanoveli JM; Department of Pharmacology, Biological Science Sector, Federal University of Paraná, Curitiba, Paraná, Brazil., Fattori V; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA., Casagrande R; Department of Pharmaceutical Sciences, Londrina State University, Avenida Robert Koch, 60, Caixa Postal 10.011, Londrina, Paraná, 86039-440, Brazil., Verri WA Jr; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil. waldiceujr@yahoo.com.br.
Source: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2026 Apr 02; Vol. 75 (1). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9508160 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-908X (Electronic) Linking ISSN: 10233830 NLM ISO Abbreviation: Inflamm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1420-908X
DOI:10.1007/s00011-026-02234-5