Intravenous injection of lipid-free apolipoprotein A-I dampens inflammation by reprogramming macrophage function.

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Title: Intravenous injection of lipid-free apolipoprotein A-I dampens inflammation by reprogramming macrophage function.
Authors: Bisoendial R; Department of Immunology, Erasmus Medical Center, 3015 GD Rotterdam, the Netherlands; Department of Rheumatology and Clinical Immunology, Maasstad Hospital, 3079 DZ Rotterdam, the Netherlands; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia; Lipid Research Group, School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address: bisoendialr@maasstadziekenhuis.nl., Kusienicka A; Department of Dermatology, Medical University of Vienna, Wien, Vienna 1090, Austria., Wielscher M; Department of Dermatology, Medical University of Vienna, Wien, Vienna 1090, Austria., Roediger B; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia; Novartis, 4056 Basel, Switzerland., Jain R; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia; Department of Dermatology, Medical University of Vienna, Wien, Vienna 1090, Austria., Mitchell A; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia., Grau G; Vascular Immunology Unit, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia., van Olden C; Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, the Netherlands., Stroes E; Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, the Netherlands., Tas S; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands., Van Eck M; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, 2333 AL Leiden, the Netherlands; Pharmacy Leiden, 2300 RA Leiden, the Netherlands., Youssef P; Rheumatology Department, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia., Cavanagh LL; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia., Rye KA; Lipid Research Group, School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia., Farlik M; Department of Dermatology, Medical University of Vienna, Wien, Vienna 1090, Austria., Weninger W; Immune Imaging Program, The Centenary Institute of Cancer Medicine and Cell Biology, Sydney, NSW 2050, Australia; Department of Dermatology, Medical University of Vienna, Wien, Vienna 1090, Austria; Discipline of Dermatology, University of Sydney, Sydney, NSW 2006, Australia; Dermatology Department, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia. Electronic address: w.weninger@meduniwien.ac.at.
Source: Cell reports [Cell Rep] 2026 Mar 31; Vol. 45 (4), pp. 117212. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117212