Polystyrene nanoplastics induce hepatic steatosis by disrupting autophagic degradation of NCoR1 and suppressing PPARα-mediated fatty acid oxidation.
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| Title: | Polystyrene nanoplastics induce hepatic steatosis by disrupting autophagic degradation of NCoR1 and suppressing PPARα-mediated fatty acid oxidation. |
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| Authors: | Fang Y; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Wei T; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Zhang Z; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Li Y; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Yang M; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Chen H; Department of Nutrition and Food Hygiene, School of Public Health, Capital Medical University, Beijing, China., Wang Y; Department of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, China., Hao R; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Li Y; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Sun Z; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China., Wang J; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China. wangji@ccmu.edu.cn.; Beijing Key Laboratory of Environmental and Aging, Capital Medical University, Beijing, 100069, China. wangji@ccmu.edu.cn. |
| Source: | Journal of nanobiotechnology [J Nanobiotechnology] 2026 Apr 02; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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