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Phosphorylated lantibiotics-producing commensals integrate into the human oral microbiome to suppress pathogens and promote microbiome homeostasis.

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Title: Phosphorylated lantibiotics-producing commensals integrate into the human oral microbiome to suppress pathogens and promote microbiome homeostasis.
Authors: Barbour A; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada. abdelahhad.barbour@utoronto.ca.; Ostia Sciences Inc, Toronto, ON, Canada. abdelahhad.barbour@utoronto.ca., Bendayan Y; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Marks C; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.; Ostia Sciences Inc, Toronto, ON, Canada., Choi YHK; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.; Ostia Sciences Inc, Toronto, ON, Canada., Oveisi M; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Callaghan M; Ostia Sciences Inc, Toronto, ON, Canada., Sun C; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Zargaran S; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Xia M; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Wood D; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada., Smith L; Department of Biology, Texas A&M University, College Station, TX, USA., McLean JS; Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA., Mazzulli T; Department of Microbiology, Sinai Health System/University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Glogauer M; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.; Ostia Sciences Inc, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.; Department of Dental Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.
Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2026 Apr 03; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phosphorylated lantibiotics-producing commensals integrate into the human oral microbiome to suppress pathogens and promote microbiome homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Barbour+A%22">Barbour A</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada. abdelahhad.barbour@utoronto.ca.; Ostia Sciences Inc, Toronto, ON, Canada. abdelahhad.barbour@utoronto.ca.<br /><searchLink fieldCode="AU" term="%22Bendayan+Y%22">Bendayan Y</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Marks+C%22">Marks C</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.; Ostia Sciences Inc, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Choi+YHK%22">Choi YHK</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.; Ostia Sciences Inc, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Oveisi+M%22">Oveisi M</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Callaghan+M%22">Callaghan M</searchLink>; Ostia Sciences Inc, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zargaran+S%22">Zargaran S</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Xia+M%22">Xia M</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wood+D%22">Wood D</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+L%22">Smith L</searchLink>; Department of Biology, Texas A&M University, College Station, TX, USA.<br /><searchLink fieldCode="AU" term="%22McLean+JS%22">McLean JS</searchLink>; Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Mazzulli+T%22">Mazzulli T</searchLink>; Department of Microbiology, Sinai Health System/University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Glogauer+M%22">Glogauer M</searchLink>; Faculty of Dentistry, University of Toronto, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.; Ostia Sciences Inc, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.; Department of Dental Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada. michael.glogauer@dentistry.utoronto.ca.
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