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Preclinical efficacy of a favipiravir and nitazoxanide combination against Rift Valley Fever Virus.

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Title: Preclinical efficacy of a favipiravir and nitazoxanide combination against Rift Valley Fever Virus.
Authors: Chaput S; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Driouich JS; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Pastorino B; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Amaral R; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Piorkowski G; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Darbon P; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Diarra C; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France., Giocanti M; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France., Néant N; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France., Grard G; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; Institut de Recherche Biomédicale des Armées, Unité de Virologie, Marseille, France., Mély S; INSERM Laboratoire P4 Jean Mérieux, Lyon, France., Lingas G; Université Paris Cité, INSERM, IAME, F-75018, Paris, France., Guedj J; Université Paris Cité, INSERM, IAME, F-75018, Paris, France., de Lamballerie X; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France., Solas C; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France., Touret F; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France. Electronic address: franck.touret@ird.fr., Nougairède A; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France. Electronic address: antoine.nougairede@univ-amu.fr.
Source: Antiviral research [Antiviral Res] 2026 May; Vol. 249, pp. 106402. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE
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  Data: Preclinical efficacy of a favipiravir and nitazoxanide combination against Rift Valley Fever Virus.
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  Data: <searchLink fieldCode="AU" term="%22Chaput+S%22">Chaput S</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Driouich+JS%22">Driouich JS</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Pastorino+B%22">Pastorino B</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Amaral+R%22">Amaral R</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Piorkowski+G%22">Piorkowski G</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Darbon+P%22">Darbon P</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Diarra+C%22">Diarra C</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Giocanti+M%22">Giocanti M</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Néant+N%22">Néant N</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Grard+G%22">Grard G</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; Institut de Recherche Biomédicale des Armées, Unité de Virologie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Mély+S%22">Mély S</searchLink>; INSERM Laboratoire P4 Jean Mérieux, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Lingas+G%22">Lingas G</searchLink>; Université Paris Cité, INSERM, IAME, F-75018, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guedj+J%22">Guedj J</searchLink>; Université Paris Cité, INSERM, IAME, F-75018, Paris, France.<br /><searchLink fieldCode="AU" term="%22de+Lamballerie+X%22">de Lamballerie X</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Solas+C%22">Solas C</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France; APHM, Hôpital La Timone, Laboratoire de Pharmacocinétique et Toxicologie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Touret+F%22">Touret F</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France. Electronic address: franck.touret@ird.fr.<br /><searchLink fieldCode="AU" term="%22Nougairède+A%22">Nougairède A</searchLink>; Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), Marseille, France. Electronic address: antoine.nougairede@univ-amu.fr.
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  Data: <searchLink fieldCode="JN" term="%228109699%22">Antiviral research</searchLink> [Antiviral Res] 2026 May; Vol. 249, pp. 106402. <i>Date of Electronic Publication: </i>2026 Apr 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8109699 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9096 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201663542%22">01663542 </searchLink><i>NLM ISO Abbreviation: </i>Antiviral Res <i>Subsets: </i>MEDLINE
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