The exonic SNP rs11676272-C risk allele mediates diet-induced obesity and reduces enhancer activation.
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| Title: | The exonic SNP rs11676272-C risk allele mediates diet-induced obesity and reduces enhancer activation. |
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| Authors: | Wang W; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China.; The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, 310058, China., Li Y; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Dong S; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Liu Y; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Guo C; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Su Y; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Tian W; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China., Hu X; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China. Xiaoyu.Hu@hbu.edu.cn.; Hebei Innovation Center for Bioengineering and Biotechnology, Hebei University, Baoding, 071002, China. Xiaoyu.Hu@hbu.edu.cn.; Hebei Basic Science Center for Biotic Interaction, Hebei University, Baoding, 071002, China. Xiaoyu.Hu@hbu.edu.cn., Wang Z; School of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding, 071002, China. zswang@hbu.edu.cn.; Hebei Innovation Center for Bioengineering and Biotechnology, Hebei University, Baoding, 071002, China. zswang@hbu.edu.cn.; Hebei Basic Science Center for Biotic Interaction, Hebei University, Baoding, 071002, China. zswang@hbu.edu.cn.; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding, 071002, China. zswang@hbu.edu.cn. |
| Source: | EMBO reports [EMBO Rep] 2026 May; Vol. 27 (9), pp. 2462-2490. Date of Electronic Publication: 2026 Apr 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.1038/s44319-026-00758-9 |
