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Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion protein.

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Title: Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion protein.
Authors: Wang Q; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Ke X; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China., Li E; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Hong D; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Cheng Z; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Li H; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China., Zhang J; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Jin T; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China., Gong R; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China., Shu B; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. shubo@wh.iov.cn., Chiu S; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China. qiux@ustc.edu.cn.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China. qiux@ustc.edu.cn.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China. qiux@ustc.edu.cn.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 May; Vol. 18 (5), pp. 1866-1883. Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion protein.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Ke+X%22">Ke X</searchLink>; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.<br /><searchLink fieldCode="AU" term="%22Li+E%22">Li E</searchLink>; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Hong+D%22">Hong D</searchLink>; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Cheng+Z%22">Cheng Z</searchLink>; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Jin+T%22">Jin T</searchLink>; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China.<br /><searchLink fieldCode="AU" term="%22Gong+R%22">Gong R</searchLink>; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.<br /><searchLink fieldCode="AU" term="%22Shu+B%22">Shu B</searchLink>; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. shubo@wh.iov.cn.<br /><searchLink fieldCode="AU" term="%22Chiu+S%22">Chiu S</searchLink>; Department of Infectious Disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China. qiux@ustc.edu.cn.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, China. qiux@ustc.edu.cn.; Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases, Hefei, Anhui, 230026, China. qiux@ustc.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 May; Vol. 18 (5), pp. 1866-1883. <i>Date of Electronic Publication: </i>2026 Apr 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s44321-026-00412-w
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        Text: English
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        StartPage: 1866
    Titles:
      – TitleFull: Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion protein.
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              M: 05
              Text: 2026 May
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