Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48.
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| Title: | Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48. |
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| Authors: | Banerjee S; Department of Zoology, University of Otago, Dunedin, New Zealand., Earl CW; Department of Zoology, University of Otago, Dunedin, New Zealand., Robson SC; Institute of Life Sciences and Healthcare, School of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, United Kingdom.; Centre for Enzyme Innovation, School of Earth and the Environment, University of Portsmouth, Portsmouth, United Kingdom., Szyszka P; Department of Zoology, University of Otago, Dunedin, New Zealand., Beck CW; Department of Zoology, University of Otago, Dunedin, New Zealand.; Genetics Otago Research Centre, University of Otago, Dunedin, New Zealand. |
| Source: | Frontiers in neurology [Front Neurol] 2026 Mar 23; Vol. 17, pp. 1777738. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-2295 |
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| DOI: | 10.3389/fneur.2026.1777738 |
