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Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48.

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Title: Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48.
Authors: Banerjee S; Department of Zoology, University of Otago, Dunedin, New Zealand., Earl CW; Department of Zoology, University of Otago, Dunedin, New Zealand., Robson SC; Institute of Life Sciences and Healthcare, School of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, United Kingdom.; Centre for Enzyme Innovation, School of Earth and the Environment, University of Portsmouth, Portsmouth, United Kingdom., Szyszka P; Department of Zoology, University of Otago, Dunedin, New Zealand., Beck CW; Department of Zoology, University of Otago, Dunedin, New Zealand.; Genetics Otago Research Centre, University of Otago, Dunedin, New Zealand.
Source: Frontiers in neurology [Front Neurol] 2026 Mar 23; Vol. 17, pp. 1777738. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101546899%22">Frontiers in neurology</searchLink> [Front Neurol] 2026 Mar 23; Vol. 17, pp. 1777738. <i>Date of Electronic Publication: </i>2026 Mar 23 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101546899 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-2295 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216642295%22">16642295 </searchLink><i>NLM ISO Abbreviation: </i>Front Neurol <i>Subsets: </i>PubMed not MEDLINE
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