Perforin-2 enhances antigen-specific CTL immune response by promoting cross presentation.

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Title: Perforin-2 enhances antigen-specific CTL immune response by promoting cross presentation.
Authors: Zha ZK; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Deng CJ; The Center of Experimental Teaching, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Shen LJ; Department of Tuberculosis, Yunnan Clinical Medical Center for Infectious Diseases, the Third People's Hospital of Kunming (The Sixth Affiliated Hospital of Dali University), Kunming, China., Liu LZ; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Huang YX; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Li YH; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Lv L; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Zhang K; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Chen LS; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Chen FE; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China., Li SA; Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China. lishengan@163.com.; Key Laboratory of Sepsis and Brain Regulation in Universities of Yunnan Province, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China. lishengan@163.com.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 09; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08705-1