High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer.

Saved in:
Bibliographic Details
Title: High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer.
Authors: Thielen N; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Wei N; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA. ning.wei@einsteinmed.edu.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, NY, USA. ning.wei@einsteinmed.edu.; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, NY, USA. ning.wei@einsteinmed.edu., Nagai E; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Houston M; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Augenlicht LH; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Shin AE; Division of Digestive and Liver Diseases, Department of Medicine, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA., Gabre JT; Division of Digestive and Liver Diseases, Department of Medicine, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA., Rustgi AK; Division of Digestive and Liver Diseases, Department of Medicine, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA., Ha G; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., LaFave LM; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Chu E; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Kitamura S; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA. seiya.kitamura@einsteinmed.edu.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, NY, USA. seiya.kitamura@einsteinmed.edu., Kuang C; Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA. chaoyuan.kuang@einsteinmed.edu.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, NY, USA. chaoyuan.kuang@einsteinmed.edu.; Department of Oncology, Albert Einstein College of Medicine, Bronx, New York, NY, USA. chaoyuan.kuang@einsteinmed.edu.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 08; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2397-768X
DOI:10.1038/s41698-026-01384-3