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CD18-targeted peptide-drug conjugate remodels the immunosuppressive tumor microenvironment of prostate cancer by selective depletion of M2 macrophages.

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Title: CD18-targeted peptide-drug conjugate remodels the immunosuppressive tumor microenvironment of prostate cancer by selective depletion of M2 macrophages.
Authors: Han IH; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea., Choi I; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea., Kim S; Twinpig Biolab Inc. R&D Center, Seoul, Republic of Korea., Lee H; Twinpig Biolab Inc. R&D Center, Seoul, Republic of Korea., Kwon M; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea., Lee WJ; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea., Bae H; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea. hbae@khu.ac.kr.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 09; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: CD18-targeted peptide-drug conjugate remodels the immunosuppressive tumor microenvironment of prostate cancer by selective depletion of M2 macrophages.
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  Data: <searchLink fieldCode="AU" term="%22Han+IH%22">Han IH</searchLink>; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+I%22">Choi I</searchLink>; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Twinpig Biolab Inc. R&D Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Twinpig Biolab Inc. R&D Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+M%22">Kwon M</searchLink>; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+WJ%22">Lee WJ</searchLink>; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+H%22">Bae H</searchLink>; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea. hbae@khu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Apr 09; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Apr 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41698-026-01377-2
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              Text: 2026 Apr 09
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