A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.

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Title: A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.
Authors: Si J; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Lv S; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China., Gao Y; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Yang Z; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China., Liang W; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China., Shen X; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Liu G; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China. liug@simt.com.cn., Su S; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China. iamssu@njupt.edu.cn., Zhu C; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China. zhuchangfeng@fudan.edu.cn.; Shanghai Institute of Liver Diseases, Shanghai, China. zhuchangfeng@fudan.edu.cn.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Apr 10; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-3155
DOI:10.1186/s12951-026-04344-y