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A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.

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Title: A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.
Authors: Si J; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Lv S; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China., Gao Y; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Yang Z; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China., Liang W; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China., Shen X; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China., Liu G; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China. liug@simt.com.cn., Su S; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China. iamssu@njupt.edu.cn., Zhu C; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China. zhuchangfeng@fudan.edu.cn.; Shanghai Institute of Liver Diseases, Shanghai, China. zhuchangfeng@fudan.edu.cn.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Apr 10; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.
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  Data: <searchLink fieldCode="AU" term="%22Si+J%22">Si J</searchLink>; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Lv+S%22">Lv S</searchLink>; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liang+W%22">Liang W</searchLink>; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shen+X%22">Shen X</searchLink>; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Institute of Liver Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Key Laboratory of Bioanalysis and Metrology for State Market Regulation, Shanghai Institute of Measurement and Testing Technology, Shanghai, China. liug@simt.com.cn.<br /><searchLink fieldCode="AU" term="%22Su+S%22">Su S</searchLink>; State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing, China. iamssu@njupt.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhu+C%22">Zhu C</searchLink>; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China. zhuchangfeng@fudan.edu.cn.; Shanghai Institute of Liver Diseases, Shanghai, China. zhuchangfeng@fudan.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 Apr 10; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s12951-026-04344-y
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: A toehold-triggered switchable three-way junction protective nanoprobe for RNase H-assisted HBV rcDNA detection.
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            NameFull: Si J
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            NameFull: Lv S
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            NameFull: Gao Y
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            NameFull: Yang Z
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            NameFull: Shen X
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            NameFull: Liu G
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            NameFull: Su S
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            – D: 10
              M: 04
              Text: 2026 Apr 10
              Type: published
              Y: 2026
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              Value: 1477-3155
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