Efficient Generation of Functional TCRαβ+ Cytotoxic T Cells from hiPSCs via Small-Molecule Modulation.
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| Title: | Efficient Generation of Functional TCRαβ+ Cytotoxic T Cells from hiPSCs via Small-Molecule Modulation. |
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| Authors: | Kubaczka C; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA., Kambli N; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA., Windisch R; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Yu K; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA., Zhao Y; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA., Wu S; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA., Frenis K; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA., Walcheck MT; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA., Falchetti M; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Najia M; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., LeBlanc ZC; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA., North TE; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA., Rowe RG; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA., Daley GQ; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Schlaeger TM; Stem Cell and Regenerative Biology Program, Boston Children's Hospital, Boston, MA 02115, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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