DNA damage drives a unique, Alzheimer's disease-relevant senescent state in neurons.

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Bibliographic Details
Title: DNA damage drives a unique, Alzheimer's disease-relevant senescent state in neurons.
Authors: Hughes JB; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Sandholm A; Buck Institute for Research on Aging, Novato, CA, USA., Croll D; Buck Institute for Research on Aging, Novato, CA, USA., Senchyna F; Buck Institute for Research on Aging, Novato, CA, USA., Schneider K; Buck Institute for Research on Aging, Novato, CA, USA., Butterfield R; Buck Institute for Research on Aging, Novato, CA, USA., McHugh TLM; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Brown I; Buck Institute for Research on Aging, Novato, CA, USA., Deguchi H; Buck Institute for Research on Aging, Novato, CA, USA., Hilsabeck TAU; Buck Institute for Research on Aging, Novato, CA, USA., Mak S; Buck Institute for Research on Aging, Novato, CA, USA., Wilson KA; Buck Institute for Research on Aging, Novato, CA, USA., Davtyan H; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Blurton-Jones M; Department of Neurobiology and Behavior, University of California, Irvine, CA, USA., Herdy J; The Salk Institute for Biological Studies, La Jolla, CA, USA., Higuchi-Sanabria R; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Gage FH; The Salk Institute for Biological Studies, La Jolla, CA, USA., Furman D; Buck Institute for Research on Aging, Novato, CA, USA., Ellerby LM; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Desprez PY; Buck Institute for Research on Aging, Novato, CA, USA.; California Pacific Medical Center, Research Institute, San Francisco, California, USA., Campisi J; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 03. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.04.02.716205