Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer.

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Title: Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer.
Authors: McCord KA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Kan E; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Hyslop S; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Xia AY; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Hofferek CJ; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Lewis JS Jr; Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ, USA., Wieland A; Department of Otolaryngology, Pelotonia Institute for Immuno-Oncology, Ohio State University Comprehensive Cancer Center, College of Medicine, Ohio State University Wexner Medical Center, Columbus, OH, USA., Hernandez DJ; Bobby R. Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.; ENT Section, Operative CareLine, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA., Sandulache VC; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Bobby R. Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.; ENT Section, Operative CareLine, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.; Center for Translational Research on Inflammatory Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA., Hudson WH; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Source: Science immunology [Sci Immunol] 2026 Apr 10; Vol. 11 (118), pp. eaec3133. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2470-9468
DOI:10.1126/sciimmunol.aec3133