Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.

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Title: Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.
Authors: Li N; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Wang PC; Department of Gynecologic Oncology, Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Pan JY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China., Xu Y; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Ye YH; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Sun RQ; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Pan SY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Ji YY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China., Zhou J; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Fan J; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Chen RX; Department of Hepatic Oncology, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Zhou SL; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Zhou ZJ; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.
Source: Cancer immunology research [Cancer Immunol Res] 2026 Jul 02; Vol. 14 (7), pp. 1186-1201.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2326-6074
DOI:10.1158/2326-6066.CIR-25-0498