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Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.

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Title: Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.
Authors: Li N; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Wang PC; Department of Gynecologic Oncology, Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Pan JY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China., Xu Y; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Ye YH; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Sun RQ; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Pan SY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Ji YY; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China., Zhou J; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Fan J; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Chen RX; Department of Hepatic Oncology, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Zhou SL; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China., Zhou ZJ; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.
Source: Cancer immunology research [Cancer Immunol Res] 2026 Jul 02; Vol. 14 (7), pp. 1186-1201.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+PC%22">Wang PC</searchLink>; Department of Gynecologic Oncology, Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Pan+JY%22">Pan JY</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ye+YH%22">Ye YH</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+RQ%22">Sun RQ</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Pan+SY%22">Pan SY</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ji+YY%22">Ji YY</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fan+J%22">Fan J</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+RX%22">Chen RX</searchLink>; Department of Hepatic Oncology, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+SL%22">Zhou SL</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+ZJ%22">Zhou ZJ</searchLink>; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University ), Ministry of Education, Shanghai, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101614637 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2326-6074 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223266066%22">23266066 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Res <i>Subsets: </i>MEDLINE
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        Value: 10.1158/2326-6066.CIR-25-0498
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        Text: English
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      – TitleFull: Tumor-Infiltrating Platelets Recruit Neutrophils to Promote Tumor Growth through the 5-HIAA-GPR35-ERK1/2 Axis in Hepatocellular Carcinoma.
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            – D: 02
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              Text: 2026 Jul 02
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