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Up-regulation of tRNA-derived miR-1274b in tears of Parkinson's disease patients.

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Title: Up-regulation of tRNA-derived miR-1274b in tears of Parkinson's disease patients.
Authors: Salvi E; Data Science Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Computational Multi-Omics of Neurological Disorders (MIND) Lab, Joint Research Platform, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Vannetiello I; Unit of Dementias and Degenerative Diseases of the Central Nervous System - Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Cazzaniga FA; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Ciullini A; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Demleitner AF; Department of Neurology, School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany., Andreasi NG; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Tomé S; Computational Multi-Omics of Neurological Disorders (MIND) Lab, Joint Research Platform, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy., Elia AE; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Leta V; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom., Lingor P; Department of Neurology, School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany; DZNE, German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Eleopra R; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Catania M; Unit of Dementias and Degenerative Diseases of the Central Nervous System - Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy. Electronic address: marcella.catania@istituto-besta.it., Devigili G; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Moda F; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy.
Source: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2026 Jun; Vol. 147, pp. 108305. Date of Electronic Publication: 2026 Apr 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Up-regulation of tRNA-derived miR-1274b in tears of Parkinson's disease patients.
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  Data: <searchLink fieldCode="AU" term="%22Salvi+E%22">Salvi E</searchLink>; Data Science Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Computational Multi-Omics of Neurological Disorders (MIND) Lab, Joint Research Platform, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Vannetiello+I%22">Vannetiello I</searchLink>; Unit of Dementias and Degenerative Diseases of the Central Nervous System - Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Cazzaniga+FA%22">Cazzaniga FA</searchLink>; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Ciullini+A%22">Ciullini A</searchLink>; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Demleitner+AF%22">Demleitner AF</searchLink>; Department of Neurology, School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Andreasi+NG%22">Andreasi NG</searchLink>; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Tomé+S%22">Tomé S</searchLink>; Computational Multi-Omics of Neurological Disorders (MIND) Lab, Joint Research Platform, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Elia+AE%22">Elia AE</searchLink>; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Leta+V%22">Leta V</searchLink>; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lingor+P%22">Lingor P</searchLink>; Department of Neurology, School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany; DZNE, German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Eleopra+R%22">Eleopra R</searchLink>; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Catania+M%22">Catania M</searchLink>; Unit of Dementias and Degenerative Diseases of the Central Nervous System - Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy. Electronic address: marcella.catania@istituto-besta.it.<br /><searchLink fieldCode="AU" term="%22Devigili+G%22">Devigili G</searchLink>; Parkinson and Movement Disorders Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Moda+F%22">Moda F</searchLink>; Unit of Laboratory Medicine, Laboratory of Clinical Pathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy.
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  Data: <searchLink fieldCode="JN" term="%229513583%22">Parkinsonism & related disorders</searchLink> [Parkinsonism Relat Disord] 2026 Jun; Vol. 147, pp. 108305. <i>Date of Electronic Publication: </i>2026 Apr 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9513583 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-5126 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213538020%22">13538020 </searchLink><i>NLM ISO Abbreviation: </i>Parkinsonism Relat Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.parkreldis.2026.108305
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        Text: English
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              Text: 2026 Jun
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