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Asy-RPA/PCR combined with One-crRNA-CRISPR/Cas12a for simultaneous detection of multiple Clarithromycin resistance mutations in Helicobacter pylori.

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Title: Asy-RPA/PCR combined with One-crRNA-CRISPR/Cas12a for simultaneous detection of multiple Clarithromycin resistance mutations in Helicobacter pylori.
Authors: Liu Y; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Nanjing Jiangning Hospital of Chinese Medicine, Nanjing, China., Chen S; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Nanjing Jiangning Hospital of Chinese Medicine, Nanjing, China., Zhang C; Affiliated Jiangning Hospital of Chinese Medicine, China Pharmaceutical University, Nanjing, China., Xue H; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China., Abubakar MU; Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China., Yin S; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Yangzhou Hongquan Hospital, Yangzhou, China., Yang X; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Fan B; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Tai P; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Xiong M; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: mengqiuxiong@163.com., Li J; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: lijingjing_li@163.com., He B; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; H. pylori Research Key Laboratory, Nanjing Medical University, Nanjing, China. Electronic address: bhe@njmu.edu.cn.
Source: Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2026 Jun; Vol. 74, pp. 102942. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101233142 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-9642 (Electronic) Linking ISSN: 15499634 NLM ISO Abbreviation: Nanomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Asy-RPA/PCR combined with One-crRNA-CRISPR/Cas12a for simultaneous detection of multiple Clarithromycin resistance mutations in Helicobacter pylori.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Nanjing Jiangning Hospital of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Nanjing Jiangning Hospital of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Affiliated Jiangning Hospital of Chinese Medicine, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xue+H%22">Xue H</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China.<br /><searchLink fieldCode="AU" term="%22Abubakar+MU%22">Abubakar MU</searchLink>; Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.<br /><searchLink fieldCode="AU" term="%22Yin+S%22">Yin S</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; Department of Laboratory Medicine, Yangzhou Hongquan Hospital, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Fan+B%22">Fan B</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Tai+P%22">Tai P</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xiong+M%22">Xiong M</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: mengqiuxiong@163.com.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address: lijingjing_li@163.com.<br /><searchLink fieldCode="AU" term="%22He+B%22">He B</searchLink>; Department of Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; H. pylori Research Key Laboratory, Nanjing Medical University, Nanjing, China. Electronic address: bhe@njmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101233142%22">Nanomedicine : nanotechnology, biology, and medicine</searchLink> [Nanomedicine] 2026 Jun; Vol. 74, pp. 102942. <i>Date of Electronic Publication: </i>2026 Apr 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101233142 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1549-9642 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215499634%22">15499634 </searchLink><i>NLM ISO Abbreviation: </i>Nanomedicine <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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