Alox8 knockout exacerbates imiquimod-induced psoriasis-like inflammation.
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| Title: | Alox8 knockout exacerbates imiquimod-induced psoriasis-like inflammation. |
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| Authors: | Palmer MA; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany. palmer@biochem.uni-frankfurt.de., Kirchhoff R; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Hahnefeld L; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Thomas D; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Elewa MAF; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., You X; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Aliraj B; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Benatzy Y; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Weigert A; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; Department for Immunity of Inflammation, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schebb NH; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Brüne B; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Apr 10; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08727-9 |
