Alox8 knockout exacerbates imiquimod-induced psoriasis-like inflammation.

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Title: Alox8 knockout exacerbates imiquimod-induced psoriasis-like inflammation.
Authors: Palmer MA; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany. palmer@biochem.uni-frankfurt.de., Kirchhoff R; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Hahnefeld L; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Thomas D; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Elewa MAF; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., You X; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Aliraj B; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Benatzy Y; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Weigert A; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; Department for Immunity of Inflammation, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Schebb NH; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Brüne B; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 10; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alox8 knockout exacerbates imiquimod-induced psoriasis-like inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Palmer+MA%22">Palmer MA</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany. palmer@biochem.uni-frankfurt.de.<br /><searchLink fieldCode="AU" term="%22Kirchhoff+R%22">Kirchhoff R</searchLink>; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Hahnefeld+L%22">Hahnefeld L</searchLink>; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Thomas+D%22">Thomas D</searchLink>; Goethe University Frankfurt, Faculty of Medicine, Institute of Clinical Pharmacology, Frankfurt, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Elewa+MAF%22">Elewa MAF</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22You+X%22">You X</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Aliraj+B%22">Aliraj B</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Benatzy+Y%22">Benatzy Y</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Weigert+A%22">Weigert A</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; Department for Immunity of Inflammation, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Schebb+NH%22">Schebb NH</searchLink>; Chair of Food Chemistry, School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Brüne+B%22">Brüne B</searchLink>; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 10; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 10.
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              Text: 2026 Apr 10
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