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Berry-derived gold nanoparticles induce integrated ROS-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells.

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Title: Berry-derived gold nanoparticles induce integrated ROS-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells.
Authors: Fagbohun OF; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA. oladapo.fagbohun@wilmington.edu., Oladipo AO; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.; Department of Mechanical, Bioresources, and Biomedical Engineering, University of South Africa, Florida Science Campus, Roodepoort, South Africa., Gao C; Mass Spectrometry and Proteomics Facility, The Ohio State University, Columbus, OH, USA., Olawoye B; Department of Food Science and Technology, Abiola Ajimobi Technical University, Ibadan, Oyo, Nigeria., Berry RS; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., Captain JC; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., Iragena O; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., McDougle X; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., Harris RJ; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., Rollins A; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA., Joseph JS; Department of Biochemistry, National Institute for Occupational Health, Division of National Health Laboratory Services, Johannesburg, South Africa.; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Johannesburg, Republic of South Africa., Fadare OA; Organic Chemistry Research Laboratory, Department of Chemistry, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria., Kincaid R; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.
Source: Cell death discovery [Cell Death Discov] 2026 Apr 10; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Berry-derived gold nanoparticles induce integrated ROS-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Fagbohun+OF%22">Fagbohun OF</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA. oladapo.fagbohun@wilmington.edu.<br /><searchLink fieldCode="AU" term="%22Oladipo+AO%22">Oladipo AO</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.; Department of Mechanical, Bioresources, and Biomedical Engineering, University of South Africa, Florida Science Campus, Roodepoort, South Africa.<br /><searchLink fieldCode="AU" term="%22Gao+C%22">Gao C</searchLink>; Mass Spectrometry and Proteomics Facility, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Olawoye+B%22">Olawoye B</searchLink>; Department of Food Science and Technology, Abiola Ajimobi Technical University, Ibadan, Oyo, Nigeria.<br /><searchLink fieldCode="AU" term="%22Berry+RS%22">Berry RS</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22Captain+JC%22">Captain JC</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22Iragena+O%22">Iragena O</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22McDougle+X%22">McDougle X</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22Harris+RJ%22">Harris RJ</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22Rollins+A%22">Rollins A</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.<br /><searchLink fieldCode="AU" term="%22Joseph+JS%22">Joseph JS</searchLink>; Department of Biochemistry, National Institute for Occupational Health, Division of National Health Laboratory Services, Johannesburg, South Africa.; Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Johannesburg, Republic of South Africa.<br /><searchLink fieldCode="AU" term="%22Fadare+OA%22">Fadare OA</searchLink>; Organic Chemistry Research Laboratory, Department of Chemistry, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria.<br /><searchLink fieldCode="AU" term="%22Kincaid+R%22">Kincaid R</searchLink>; Department of Biology, Center for Agriculture and Natural Sciences, Wilmington College, Wilmington, OH, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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