View in EDS HTML Full Text PDF Full Text

The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.

Saved in:
Bibliographic Details
Title: The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.
Authors: Ambrosi C; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland., Pfaendler R; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland., Eleftheriou K; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Butz S; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland., Recchia D; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Bao X; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Cardoso da Silva R; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Kupfer N; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Lagerwaard IM; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Vlaming H; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Schmolka N; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Bhardwaj V; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands., Baubec T; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland. t.baubec@uu.nl.; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands. t.baubec@uu.nl.
Source: The EMBO journal [EMBO J] 2026 May; Vol. 45 (10), pp. 3430-3443. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41963556
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ambrosi+C%22">Ambrosi C</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pfaendler+R%22">Pfaendler R</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Eleftheriou+K%22">Eleftheriou K</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Butz+S%22">Butz S</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Recchia+D%22">Recchia D</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland.; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bao+X%22">Bao X</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cardoso+da+Silva+R%22">Cardoso da Silva R</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kupfer+N%22">Kupfer N</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lagerwaard+IM%22">Lagerwaard IM</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vlaming+H%22">Vlaming H</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schmolka+N%22">Schmolka N</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bhardwaj+V%22">Bhardwaj V</searchLink>; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Baubec+T%22">Baubec T</searchLink>; Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland. t.baubec@uu.nl.; Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, Utrecht, The Netherlands. t.baubec@uu.nl.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2026 May; Vol. 45 (10), pp. 3430-3443. <i>Date of Electronic Publication: </i>2026 Apr 10.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8208664 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2075 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202614189%22">02614189 </searchLink><i>NLM ISO Abbreviation: </i>EMBO J <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41963556
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s44318-026-00768-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3430
    Titles:
      – TitleFull: The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ambrosi C
      – PersonEntity:
          Name:
            NameFull: Pfaendler R
      – PersonEntity:
          Name:
            NameFull: Eleftheriou K
      – PersonEntity:
          Name:
            NameFull: Butz S
      – PersonEntity:
          Name:
            NameFull: Recchia D
      – PersonEntity:
          Name:
            NameFull: Bao X
      – PersonEntity:
          Name:
            NameFull: Cardoso da Silva R
      – PersonEntity:
          Name:
            NameFull: Kupfer N
      – PersonEntity:
          Name:
            NameFull: Lagerwaard IM
      – PersonEntity:
          Name:
            NameFull: Vlaming H
      – PersonEntity:
          Name:
            NameFull: Schmolka N
      – PersonEntity:
          Name:
            NameFull: Bhardwaj V
      – PersonEntity:
          Name:
            NameFull: Baubec T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1460-2075
          Numbering:
            – Type: volume
              Value: 45
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: The EMBO journal
              Type: main
ResultId 1