Computational and umbrella sampling analysis of HER2 D769H and D769Y variants: mutation-specific structural alterations and drug interactions in breast cancer.

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Title: Computational and umbrella sampling analysis of HER2 D769H and D769Y variants: mutation-specific structural alterations and drug interactions in breast cancer.
Authors: Loganathan T; Laboratory for Integrative Genomics, Department of Integrative Biology, School of BioSciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu, 632014, India., Doss GPC; Laboratory for Integrative Genomics, Department of Integrative Biology, School of BioSciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu, 632014, India. georgepriyadoss@vit.ac.in.
Source: Journal of biological physics [J Biol Phys] 2026 Apr 11; Vol. 52 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Country of Publication: Netherlands NLM ID: 0417731 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-0689 (Electronic) Linking ISSN: 00920606 NLM ISO Abbreviation: J Biol Phys Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-0689
DOI:10.1007/s10867-026-09709-w