Hypoxia-induced BTN3A2 promotes glioma progression and chemoresistance via AKT/SP1/RAD51-mediated DNA damage.
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| Title: | Hypoxia-induced BTN3A2 promotes glioma progression and chemoresistance via AKT/SP1/RAD51-mediated DNA damage. |
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| Authors: | Xu Z; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of Neurosurgery, Pu'er People's Hospital, Kunming University of Science and Technology Affiliated Hospital, Yunnan, China., Pu S; School of Biosciences, University of Birmingham, Birmingham, UK., Wu J; Department of Neurosurgery, Pu'er People's Hospital, Kunming University of Science and Technology Affiliated Hospital, Yunnan, China., Yuan S; Department of Respiratory and Critical Care Medicine, Pu'er People's Hospital, Kunming University of Science and Technology Affiliated Hospital, Yunnan, China., Huang X; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China., Tian J; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China., Li X; Department of Neurosurgery, Pu'er People's Hospital, Kunming University of Science and Technology Affiliated Hospital, Yunnan, China., Liu B; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China., Yu X; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China., Zhao J; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China., Shi F; Department of Neurosurgery, Pu'er People's Hospital, Kunming University of Science and Technology Affiliated Hospital, Yunnan, China. shifengcai@163.com., Chen X; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China. chenxi5@kmmu.edu.cn., Pu J; Department of Neurosurgery, The second Affiliated Hospital of Kunming Medical University, Kunming, China. pujun@kmmu.edu.cn. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Apr 11; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08729-7 |