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Age-associated regulation of chondrocyte hypertrophy in osteoarthritis: Mechanisms, therapeutic implications, and cartilage fate reprogramming.

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Title: Age-associated regulation of chondrocyte hypertrophy in osteoarthritis: Mechanisms, therapeutic implications, and cartilage fate reprogramming.
Authors: Ha JS; Department of Biomedical Laboratory Science, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Jo A; Department of Smart Foods and Drugs, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Yeo EJ; Department of Smart Foods and Drugs, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Kim YW; Department of Biomedical Laboratory Science, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Lim JY; Department of Biomedical Laboratory Science, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea; Institute of Digital Anti-aging Healthcare, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Yun S; Department of Biotechnology, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea., Moon SW; Department of Orthopaedic Surgery, Inje University Haeundae Paik Hospital, 875, Haeun-daero, Busan 48108, Republic of Korea., Choi WS; Department of Biomedical Laboratory Science, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea; Department of Smart Foods and Drugs, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea; Institute of Digital Anti-aging Healthcare, Inje University, 197, Inje-ro, Gimhae 50834, Republic of Korea. Electronic address: wansuchoi@inje.ac.kr.
Source: Ageing research reviews [Ageing Res Rev] 2026 Jun; Vol. 118, pp. 103139. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 101128963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9649 (Electronic) Linking ISSN: 15681637 NLM ISO Abbreviation: Ageing Res Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-9649
DOI:10.1016/j.arr.2026.103139