5' UTR length shapes alternative N-terminal protein isoforms across cancers and in rare disease.

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Title: 5' UTR length shapes alternative N-terminal protein isoforms across cancers and in rare disease.
Authors: Ly J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Smith EM; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Di Bernardo M; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Tao YF; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Black EM; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Khalizeva E; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Cheeseman IM; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. icheese@wi.mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. icheese@wi.mit.edu.
Source: EMBO reports [EMBO Rep] 2026 May; Vol. 27 (10), pp. 2823-2843. Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-026-00776-7