Chromosomal instability promotes cell migration and invasion via EFEMP1 secretion into extracellular vesicles.
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| Title: | Chromosomal instability promotes cell migration and invasion via EFEMP1 secretion into extracellular vesicles. |
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| Authors: | Zheng S; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Tian R; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Siburian M; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Haider Rubio A; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Liu Y; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Wardenaar R; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Shirzai M; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Kempe L; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Dijkstra E; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands.; UMCG Microscopy Centre, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Warszawik E; Department of Biomaterials & Biomedical Technology, University Groningen, University of Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Suarez Peredo Rodriguez M; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Sjollema K; UMCG Microscopy Centre, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Bakker PL; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Rijn PV; Department of Biomaterials & Biomedical Technology, University Groningen, University of Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Borghesan M; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Paridaen JT; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands., Santaguida S; Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Foijer F; European Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL-9713 AV, Groningen, the Netherlands. f.foijer@umcg.nl. |
| Source: | The EMBO journal [EMBO J] 2026 May; Vol. 45 (10), pp. 3471-3499. Date of Electronic Publication: 2026 Apr 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00766-4 |
