Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging.
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| Title: | Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging. |
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| Authors: | Mishra M; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA., Kim HH; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA., Youm YH; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA., Gonzalez-Hurtado E; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA., Zaitsev K; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Dlugos T; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA., Shchukina I; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Gliniak C; Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ravussin E; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Mohanty S; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Shaw AC; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA., Scherer PE; Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX, USA., Artyomov MN; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Dixit VD; Department of Pathology, Yale School of Medicine, New Haven, CT, USA. vishwa.dixit@yale.edu.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA. vishwa.dixit@yale.edu.; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA. vishwa.dixit@yale.edu.; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA. vishwa.dixit@yale.edu. |
| Source: | Nature aging [Nat Aging] 2026 May; Vol. 6 (5), pp. 1064-1078. Date of Electronic Publication: 2026 Apr 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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