Early life exposure to N-nitrosamine drives genotoxicity, mutagenesis, and tumorigenesis in DNA repair-deficient mice.
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| Title: | Early life exposure to N-nitrosamine drives genotoxicity, mutagenesis, and tumorigenesis in DNA repair-deficient mice. |
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| Authors: | Volk LB; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Norales M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Karjane C; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Corrigan JJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Alcaraz AJ; Department of Biology, University of Ottawa, Ottawa, Canada., Pribyl LJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Bugher NA; Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Blawas M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA., Dulski I; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Arunachalam E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Gubina N; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Michelsen E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Pichappan K; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Yakimchuk N; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA., Swanson M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Ma D; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Levine SS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Plata DL; Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Croy RG; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Samson LD; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Essigmann JM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Yauk CL; Department of Biology, University of Ottawa, Ottawa, Canada., Carrasco SE; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, Rockefeller University, New York, NY, USA., Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. bevin@mit.edu. |
| Source: | Nature communications [Nat Commun] 2026 Apr 14; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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