Real-world effectiveness and tolerability of highly purified cannabidiol in patients with monogenic developmental and epileptic encephalopathies with highly active epilepsy.

Saved in:
Bibliographic Details
Title: Real-world effectiveness and tolerability of highly purified cannabidiol in patients with monogenic developmental and epileptic encephalopathies with highly active epilepsy.
Authors: Cerulli Irelli E; Department of Human Neurosciences, Sapienza University, Rome, Italy. Electronic address: emanueleci@hotmail.it., Mazzeo A; Department of Human Neurosciences, Sapienza University, Rome, Italy., Caraballo RH; Department of Neurology, Hospital de Pediatría 'Prof. Dr. Juan P Garrahan', Buenos Aires, Argentina., Perulli M; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Moloney PB; Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland., Peña-Ceballos J; Department of Neurology, Beaumont Hospital, Dublin, Ireland., Simeone N; Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy., Mieszczanek TS; Danish Epilepsy Centre, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Dianalund, Denmark., Marini L; Department of Clinical and Experimental Medicine, University of Pisa 56100 Pisa, Italy., Licchetta L; IRCCS Istituto delle Scienze Neurologiche di Bologna, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy., De Giorgis V; Brain and Behavioral Sciences Department, University of Pavia, Pavia, Italy; Childhood and Adolescence Epilepsy Center, Department of Child Neurology and Psychiatry, IRCCS Mondino Foundation, ERN EpiCARE Full Member, Pavia, Italy., Reyes Valenzuela G; Department of Neurology, Hospital de Pediatría 'Prof. Dr. Juan P Garrahan', Buenos Aires, Argentina., Casellato S; Department of Woman's and Child's Health, Child Neuropsichiatry Unit, Center of Pediatric Epilepsies, AOU Sassari, University of Sassari, Italy., Cesaroni E; Child Neurology and Psychiatric Unit, Pediatric Hospital G. Salesi, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy., Operto FF; Department of Science of Health, School of Medicine, University of Catanzaro, Catanzaro, Italy., Domínguez-Carral J; Epilepsy Unit, Department of Child Neurology, Institut de Recerca Sant Joan de Déu, Member of the European Reference Network (ERN) for rare and complex epilepsies (EpiCARE), Barcelona, Spain., Ramírez-Camacho A; Epilepsy Unit, Department of Child Neurology, Institut de Recerca Sant Joan de Déu, Member of the European Reference Network (ERN) for rare and complex epilepsies (EpiCARE), Barcelona, Spain., Ferretti A; Department of Neuroscience, Mental Health & Sense Organs (NESMOS), Faculty of Medicine & Psychology, Sant'Andrea Hospital, 00198 Rome, Italy., Santangelo G; Child Neuropsychiatry Department, ISMEP-ARNAS Civico, 90100 Palermo, Italy., Aledo-Serrano A; Epilepsy Unit, Clinical Neurosciences Department, Blua Sanitas Valdebebas Hospital, Madrid, Spain., Rüegger A; Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland., Mancardi MM; IRCCS Istituto Giannina Gaslini, Member of the European Reference Network (ERN) for rare and complex epilepsies (EpiCARE), Genoa, Italy., Prato G; IRCCS Istituto Giannina Gaslini, Member of the European Reference Network (ERN) for rare and complex epilepsies (EpiCARE), Genoa, Italy., Riva A; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Bergonzini L; IRCCS Istituto delle Scienze Neurologiche di Bologna, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Bologna, Italy., Cordelli DM; IRCCS Istituto delle Scienze Neurologiche di Bologna, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Bologna, Italy., Bonanni P; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano 31015, Italy., Bisulli F; IRCCS Istituto delle Scienze Neurologiche di Bologna, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Di Gennaro G; IRCCS 'Neuromed', Pozzilli 86077 Isernia, Italy., Matricardi S; Department of Pediatrics, University of Chieti-Pescara, 66100 Chieti, Italy., Striano P; IRCCS Istituto Giannina Gaslini, Member of the European Reference Network (ERN) for rare and complex epilepsies (EpiCARE), Genoa, Italy; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Delanty N; Department of Neurology, Beaumont Hospital, Dublin, Ireland; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland; Research Ireland FutureNeuro Centre, Dublin, Ireland., Marini C; Child Neurology and Psychiatric Unit, Pediatric Hospital G. Salesi, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy., Battaglia DI; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Di Bonaventura C; Department of Human Neurosciences, Sapienza University, Rome, Italy., Ramantani G; Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland., Gardella E; Danish Epilepsy Centre, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), Dianalund, Denmark; University of Southern Denmark, Odense, Denmark., Orsini A; Department of Clinical and Experimental Medicine, University of Pisa 56100 Pisa, Italy., Coppola A; Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy.
Corporate Authors: GENE-CBD study group
Source: Epilepsy & behavior : E&B [Epilepsy Behav] 2026 Jul; Vol. 180, pp. 111036. Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 100892858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-5069 (Electronic) Linking ISSN: 15255050 NLM ISO Abbreviation: Epilepsy Behav Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1525-5069
DOI:10.1016/j.yebeh.2026.111036