The weight-loss-independent hepatoprotective benefits of semaglutide are orchestrated by intrahepatic sinusoidal endothelial GLP-1 receptors.
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| Title: | The weight-loss-independent hepatoprotective benefits of semaglutide are orchestrated by intrahepatic sinusoidal endothelial GLP-1 receptors. |
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| Authors: | Gonzalez-Rellan MJ; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Riobello C; Liver Metabolism and Disorders Laboratory, CIMUS University of Santiago de Compostela, A Coruña, Spain; Gene Regulatory Control in Disease, CIMUS University of Santiago de Compostela, A Coruña, Spain., Fang S; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Martins da Silva E; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Koehler JA; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Shang R; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Hammoud R; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Cao X; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada., Varela-Rey M; Liver Metabolism and Disorders Laboratory, CIMUS University of Santiago de Compostela, A Coruña, Spain; Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, A Coruña, Spain., Drucker DJ; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON, Canada. Electronic address: drucker@lunenfeld.ca. |
| Source: | Cell metabolism [Cell Metab] 2026 Jul 07; Vol. 38 (7), pp. 1334-1353.e7. Date of Electronic Publication: 2026 Apr 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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